beta-Lactamases in laboratory and clinical resistance.
نویسندگان
چکیده
منابع مشابه
Extended-spectrum beta-lactamases: implications for the clinical laboratory and therapy.
Production of extended-spectrum beta-lactamase (ESBL) is one of the most important resistance mechanisms that hamper the antimicrobial treatment of infections caused by Enterobacteriaceae. ESBLs are classified into several groups according to their amino-acid sequence homology. While TEM and SHV enzymes were the most common ESBLs in the 1990s, CTX-M enzymes have spread rapidly among Enterobacte...
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We report the genetic characterization of 15 Klebsiella pneumoniae (KP) and 4 isolates of K. oxytoca (KO) from clinical cases in dogs and cats and showing extended-spectrum cephalosporin (ESC) resistance. Extended spectrum beta-lactamase (ESBL) and AmpC genes, plasmid-mediated quinolone resistance (PMQR) and co-resistances were investigated. Among KP isolates, ST101 clone was predominant (8/15,...
متن کاملCo Existence of Ampc and Extended Spectrum Beta Lactamases Resistance in Metallo Beta Lactamases Producing Strains of Pseudomonas Aeruginosa
Pseudomonas aeruginosa is one of the commonest multi drug resistant bacteria causing nosocomial infection and Metallo-Beta-Lactamase production is one of the important reasons. The following study was conducted to determine incidence of MBL producing P.aeruginosa. and co existence of AmpC and ESBL production. Screening for MBL was done using imipenem disk and all the isolates found resistant we...
متن کاملFrequency of E. coli clinical isolates producing blaSHV and blaTEM extended-spectrum beta-lactamases
Introduction: Production of extended-spectrum beta-lactamase enzymes (ESBLs) in E. coli creates many problems for patients. These enzymes are located on transferable elements and can hydrolyze penicillins, broad-spectrum cephalosporins, and aztreonam. This study aimed to determine the clinical isolates of E. coli producing ESBLs of blaSHV and blaTEM in the city of Zanjan. Methods: This cross...
متن کاملDetection of extended spectrum beta lactamases, ampc beta lactamases and metallobetalactamases in clinical isolates of ceftazidime resistant Pseudomonas Aeruginosa
We studied the prevalence of ceftazidime resistance in Pseudomonas aeruginosa and the rates of extended-spectrum β-lactamase (ESBL), AmpC β-lactamase (AmpC) and metallo-β-lactamase (MBL) production among the ceftazidime resistant Pseudomonas aeruginosa. A very high rate of MBL production was observed, which suggested it to be an important contributing factor for ceftazidime resistance among Pse...
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ژورنال
عنوان ژورنال: Clinical microbiology reviews
سال: 1995
ISSN: 0893-8512
DOI: 10.1128/cmr.8.4.557-584.1995